A great deal of Eksigent's success is the result of the company's unique appreciation of micro-scale technology. While other companies consider product incorporation strategies for their existing patent portfolios, Eksigent studies the bottlenecks and frustrations affecting lab productivity and selects and develops new micro-technologies based on their problem-solving capabilities. This approach drives internal innovation, shatters old product categories and creates new ones, and generates orders-of-magnitude laboratory productivity improvements in our customers' laboratories.
Eksigent's applied technologies come from technology transfer, in-licensing, and in-house development and invention. These technologies have enabled Eksigent to lead the way in the research community's transition from conventional to nanoscale HPLC, the adoption of MS-coupled liquid-phase protein mixture separation as a routine proteomic research method, the recent scientific re-appraisal of micro LC, and the development of more accurate and convenient ways to deliver biopharmaceutical agents.
Our scientists and engineers pride themselves on taking a novel approach to all of the systems and instruments that we design and manufacture. And the result is evident in the suite of technological innovations that result in systems that are simply unparalleled in performance.
Microfluidic Flow Control (MFC) Technology
Adapting technology based on the way things have been done in the past is not Eksigent’s methodology. By taking a novel approach to development, our Microfluidic Flow Control (MFC) pump technology eliminates the flow splitters found in traditional HPLC instruments, providing researchers the ability to immediately adjust flow rates for delivering accurate, consistent and precise analyses, run-after-run.
Rather than utilizing positive displacement pistons to regulate flow, this entirely new pumping principle uses continuous feedback to an electronically controlled pressure source to maintain precise nanoscale flow rates as low as 20 nL/min without flow splitting. By combining true microfluidic pump control with direct feedback of flow rate, the system eliminates the flow inaccuracies and plumbing problems caused by splitter-based systems.
MFC systems can precisely control the flow rate:Eksigent’s MFC capability allows the flow rate to be changed rapidly for higher speed sample loading or for extended MS/MS analysis (peak parking) to identify co-eluting and low abundance peptides. After the gradient, DFC can automatically increase the flow rate to accelerate flushing and reduce the lag time between sample runs. Dynamic Flow Control can be triggered with one mouse click or by a signal from the mass spectrometer, eliminating the complexity of previous approaches requiring additional pumps or valves.
Learn more about MFC technology works.
